You are limited to 8 items, forcing you to constantly swap and curate your build.
Here is the breakdown of what Repentance adds to the base Rebirth : The Binding Of Isaac Repentance Full
If you own Rebirth , Afterbirth , and Afterbirth+ , Repentance is the ultimate upgrade. But if you’re new: You are limited to 8 items, forcing you
The full version includes nearly a decade's worth of development, totaling: You are limited to 8 items