There are two ways to run the game: from a USB drive or directly from the internal HDD. Internal HDD is recommended for load times.
The Xbox 360's Xenon CPU is weak by modern standards. Here is the technical reality of performance: Mx vs ATV Alive -Jtag RGH-
If you have a modded console, install both. Use Mx vs ATV for the Career Mode unlock. Use ATV Alive for the "Free Ride" chaos sessions with friends. There are two ways to run the game: