First, the most straightforward and officially supported method:

1. The Official "Portable" Solution: Microsoft 365 for the Web

: Files are saved to OneDrive , making them accessible from any device. 2. Mobile Apps (The Smartphone Option)

. Microsoft does not offer an official "portable" version of Office 365 that you can run from a USB drive without installation. Because Office 365 is closed-source paid software, its licensing specifically forbids the alterations required to make it truly portable.